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SUPREMO
GLOBAL
SUPREMO Trial
A randomised phase III trial assessing the role of chest wall irradiation in women.
- Status
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No Longer Recruiting
- Objectives
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To determine the effect of: Ipsilateral chest wall irradiation following mastectomy and axillary clearance for women with operable breast cancer at ‘intermediate risk’ of loco-regional recurrence.
- Subjects
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- Endpoints
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On the primary endpoint of: Overall survival, Secondary endpoints: Chest wall recurrence, Regional recurrence, Disease-free survival, Metastasis-free survival, Cause of death (Breast cancer, Intercurrent disease [cardiovascular and non-cardiovascular]), Acute and late morbidity, Quality of Life, Cost effectiveness
- Trial Period
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Follow up 10 years
- Lead Principal Investigator
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Dr Ian Kunkler (Western General Hospital,Edinburgh, Scotland, UK), Dr Peter Canney (Western Infirmary, Glasgow, Scotland, UK)
- Target Sample Size
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3700
- Regimen
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Non (operation →Radiation therapy)
- Source of Funding
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Supported by JBCRG, in Japan.
- Conference Presentation
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- Articles and Publications
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- UMIN-ID
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- jRCT
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- Memo
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- COI Disclosure
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