-
JBCRG-04TR (Blood sample)
Translational research on capecitabine as a postoperative adjuvant chemotherapy in breast cancer patients pathologically confirmed to have residual tumors after preoperative chemotherapy: Phase-III comparative study (JBCRG-04) (CREATE-X)
- Status
-
No Longer Recruiting
- Objectives
-
The purpose of this study is to explore predictive factors for the treatment response or adverse effects of the multidrug chemotherapy containing anthracycline, taxane and/or capecitabine or hormonal therapy as adjuvant therapy and to investigate novel prognostic markers. In addition, metastatic tumor biological profile will be examined, which helps to understand biology of metastasis in breast cancer patients. In this research protocol, genotyping of patients using blood cells, somatic alterations of genome and epigenome, and gene expression profile in circulating tumor cells and tumor tissue samples will be examined.
- Subjects
-
- Endpoints
-
- Trial Period
-
- Lead Principal Investigator
-
- Target Sample Size
-
- Regimen
-
- Source of Funding
-
Japan Breast Cancer Research Group(JBCRG)
- Conference Presentation
-
- Articles and Publications
-
- UMIN-ID
-
- jRCT
-
- Memo
-
- COI Disclosure
-
